Affiliation:
1. Department of Biosurgery and Surgical Technology, St Mary's Hospital, Imperial College London, London, UK
2. Department of Histopathology, St Mary's Hospital, Imperial College London, London, UK
Abstract
Abstract
Background
Staples are made of titanium, which elicits minimal tissue reaction. The authors have encountered foreign body reaction associated with stapled human gastrointestinal anastomoses, although the literature has no reports of this. The aim of this study was to identify the refractile foreign materials causing this reaction.
Methods
Histological sections were taken from 14 gastrointestinal specimens from patients with a history of a stapled anastomosis within the specimen excised. These were reviewed by light and polarization microscopy. Scanning electron microscopy and energy dispersive X-ray analysis were carried out on these sections, staples and stapler cartridges used for gastrointestinal surgery.
Results
Foreign bodies rich in fluorine were found in three patients, and those rich in carbon in 12. Other elements identified included oxygen, calcium, sodium, potassium, magnesium, aluminium and silicon. One specimen was found to contain titanium with no surrounding foreign body reaction. Stapler cartridges contained carbon, oxygen, fluorine, calcium, sodium, potassium, magnesium, aluminium, silicon and traces of titanium. Staples were composed of pure titanium with some fibrous material on the surface containing elements found in stapler cartridges.
Conclusion
The presence of foreign body reaction was confirmed in stapled human gastrointestinal anastomoses. The source of refractile materials eliciting this reaction was the stapler cartridges.
Publisher
Oxford University Press (OUP)
Reference16 articles.
1. Colonic anastomosis with the nickel–titanium temperature-dependent memory-shape device;Nudelman;Am J Surg,2002
2. Stapled versus handsewn methods for colorectal anastomosis surgery;Lustosa;Cochrane Database Syst Rev,2001
3. Handsewn or stapled esophagogastric anastomoses after esophagectomy for cancer: meta-analysis of randomized controlled trials;Urschel;Dis Esophagus,2001
4. Impact of microscopic foreign debris on post-surgical complications;Truscott;Surg Technol Int,2004
Cited by
18 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献