Frontline treatment with the combination obinutuzumab ± chlorambucil for chronic lymphocytic leukemia outside clinical trials: Results of a multinational, multicenter study by ERIC and the Israeli CLL study group

Author:

Herishanu Yair12ORCID,Shaulov Adir3,Fineman Riva4,Bašić‐Kinda Sandra5,Aviv Ariel67,Wasik‐Szczepanek Ewa8,Jaksic Ozren9,Zdrenghea Mihnea10,Greenbaum Uri11,Mandac Inga12,Simkovic Martin13,Morawska Marta14,Benjamini Ohad215,Spacek Martin16,Nemets Anatoly17,Bairey Osnat18,Trentin Livio19,Ruchlemer Rosa20,Laurenti Luca21,Stanca Ciocan Oana22,Doubek Michael23,Shvidel Lev2425,Dali Nagib26,Mirás Fátima27,De Meûter Anne28,Dimou Maria29,Mauro Francesca R.30,Coscia Marta31,Bumbea Horia32,Szász Róbert33,Tadmor Tamar34,Gutwein Odit35,Gentile Massimo36,Scarfò Lydia3738,Tedeschi Alessandra39,Sportoletti Paolo40,Gimeno Vázquez Eva41,Marquet Juan42,Assouline Sarit43,Papaioannou Maria44,Braester Andrei45,Levato Luciano46,Gregor Michael47,Rigolin Gian M.48,Loscertales Javier49,Medina Perez Angeles50,Nijziel Marten R.51,Popov Viola M.52,Collado Rosa53,Slavutsky Irma54,Itchaki Gilad18,Ringelstein Shimrit4,Goldschmidt Neta3,Perry Chava12,Levi Shai1,Polliack Aaron3,Ghia Paolo3738

Affiliation:

1. Department of HematologyTel Aviv Sourasky Medical Center Tel Aviv Israel

2. Sackler Faculty of MedicineTel Aviv University Tel‐Aviv Israel

3. Hadassah Hebrew University Medical Center Jerusalem Israel

4. Department of HematologyRambam Health Care Campus Haifa Israel

5. University Hospital Centre Zagreb Zagreb Croatia

6. Department of HematologyHaEmek Medical Center Afula Israel

7. Faculty of MedicineTechnion Israel Institute of Technology Haifa Israel

8. Department of Hematooncologyand Bone Marrow Transplantation Medical University Lublin Poland

9. Dubrava University Hospital Zagreb Croatia

10. Iuliu Hatieganu University of Medicine and Pharmacy Cluj‐Napoca Romania

11. Ben‐Gurion University, Soroka University Medical Center Beer Sheva Israel

12. Clinical Hospital Merkur Zagreb Croatia

13. University Hospital and Medical School Hradec Kralove Hradec Kralove Czech Republic

14. St. John's Cancer Center Lublin Poland

15. Hematology DivisionChaim Sheba Medical Center Ramat Gan Israel

16. Charles University and General Hospital in Prague Prague Czech Republic

17. Barzilai University Medical Center Ashkelon Israel

18. Rabin Medical Center, Beilinson Hospital; Sackler Faculty of MedicineTel Aviv University Tel Aviv Israel

19. Hematology UnitUniversity of Padua Padua Italy

20. Department of HematologyShaare Zedek Medical Center Jerusalem Israel

21. Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy

22. Coltea Clinical Hospital Bucharest Romania

23. Department of Internal Medicine‐Hematology and OncologyMedical Faculty of Masaryk University and University Hospital Brno Brno Czech Republic

24. Department of HematologyKaplan Medical Center Rehovot Israel

25. Hebrew University of Jerusalem Jerusalem Israel

26. Ziv Medical Center Safed Israel

27. Hospital 12 de Octubre Madrid Spain

28. Institut Jules Bordet Brussels Belgium

29. Hematology Section ‐ 1st Department Of Propaedeutic Internal MedicineLaikon Hospital Athens Greece

30. Hematology, Department of Translational and Precision MedicineSapienza University, Policlinico Umberto I Rome Italy

31. Department of Molecular Biotechnology and Health SciencesUniversity of Torino Torino Italy

32. Emergency University Clinical Hospital Bucharest Romania

33. Division of Hematology, Department of Internal Medicine, Faculty of MedicineUniversity of Debrecen Debrecen Hungary

34. HematologyBnai Zion Medical Center Haifa Israel

35. Assaf Ha'Rofeh Tsrifin Israel

36. Hematology Unit and Biotechnology Research Unit, A.O. of Cosenza Cosenza Italy

37. Division of Experimental OncologyIRCCS Ospedale San Raffaele Milan Italy

38. Università Vita‐Salute San Raffaele Milan Italy

39. Department of Haematology, Niguarda Cancer CenterASST Grande Ospedale Metropolitano Niguarda Milan Italy

40. Institute of Hematology and Center for Hemato‐Oncological Research, Ospedale S. Maria della Misericordia, University of Perugia Perugia Italy

41. Hospital del Mar Barcelona Spain

42. Hematology and HemotherapyHospital Universitario Ramón y Cajal Madrid Spain

43. Division of HematologyJewish General Hospital, Montreal Quebec Canada

44. First Department of Internal Medicine, Division of HaematologyAHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece

45. Galilee Medical Center Nahariya Israel

46. Department Hematology‐OncologyAzienda Ospedaliera Pugliese‐Ciaccio Catanzaro Italy

47. Division of HematologyCantonal Hospital of Lucerne Lucerne Switzerland

48. Hematology Section, Department of Medical SciencesUniversity of Ferrara‐Azienda Ospedaliera‐Universitaria di Ferrara, University of Ferrara Ferrara Italy

49. IIS‐IP, Hospital Universitario de La Princesa Madrid Spain

50. Hospital Costa del Sol Marbella Spain

51. Maxima Medical Center Eindhoven/Veldhoven Eindhoven Netherlands

52. HematologyColentina Clinical Hospital Bucharest Romania

53. Hospital General Universitario Valencia Spain

54. Hospital Alvarez Buenos Aires Argentina

Publisher

Wiley

Subject

Hematology

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