A novel synthesis of [2-14C]2,5-dichloropyrimidine

Author:

Tran Scott B.1,Maxwell Brad D.1,Wu Hong2,Bonacorsi Samuel J.1

Affiliation:

1. Department of Chemical Synthesis, Radiochemistry Group, Bristol-Myers Squibb; Pharmaceutical Research and Development; P.O. Box 4000; Princeton; NJ; 08543; USA

2. Discovery Chemistry, Bristol-Myers Squibb; Pharmaceutical Research and Development; P.O. Box 4000; Princeton; NJ; 08543; USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference9 articles.

1. The University of Michigan website Chemistry on the Pyrimidine Ring http://deepblue.lib.umich.edu/bitstream/2027.42/62242/1/riderl_2.pdf

2. D. J. Brown R. F. Evans W. B. Cowden M. D. Fenn Chemistry of Heterocyclic Compounds: The Pyrimidines

3. Synthesis and antiviral evaluation of some β-l-2′,3′-dideoxy-5-chloropyrimidine nucleosides and pronucleotides

4. The DrugBank website http://www.drugbank.ca/drugs?type=small

5. This work was presented as a poster at the International Isotope Society 25 th Northeast US Chapter Symposium held October 21-22, 2010 in Morristown, NJ

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