Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndrome-Reference-Cited by-同舟云学术

Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndrome

Published:2021-01-31 Issue:9 Volume:236 Page:6362-6375
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J Cell Physiol

Author:

Mao Zhanrui¹,Li Ting²,Zhao Hui¹,Wang Xiaoyan³,Kang Yixin¹,Kang Yani¹^ORCID

Affiliation:

1. School of Biomedical Engineering, Bio‐ID Center Shanghai Jiao Tong University Shanghai China

2. Department of Obstetrics and Gynecology Yuncheng Central Hospital Yuncheng Shanxi China

3. Shanghai Center for Systems Biology Shanghai Jiao Tong University Shanghai China

Funder

Natural Science Foundation of Shanghai

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.30309

Reference39 articles.

1. Cytochrome P450 (CYP) 2W1 affect steroid secretion in adrenocortical cell line and tumor tissues

2. Polycystic ovary syndrome

3. Loss of methylation activates Xist in somatic but not in embryonic cells.

4. Metabolic syndrome in women with polycystic ovary syndrome

5. Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability

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