Frontline clinical diagnosis—FTIR on pancreatic cancer

Author:

Duckworth Edward1ORCID,Mortimer Matthew2,Al‐Sarireh Bilal2,Kanamarlapudi Venkateswarlu1ORCID,Roy Debdulal1ORCID

Affiliation:

1. Swansea University Swansea Wales UK

2. Morriston Hospital Morriston Wales UK

Abstract

AbstractObjectiveAccurate, easily accessible and economically viable cancer diagnostic tools are pivotal in improving the abysmal 5% survival rate of pancreatic cancer.MethodsA novel, affordable, non‐invasive diagnostic method has been developed by combining measurement precision of infrared spectroscopy with classification using machine learning tools.ResultsDiagnosis accuracy as high as 90% has been achieved. The study investigated urine and blood from pancreas cancer patients and healthy volunteers, and significantly improved accuracy by focusing on sweet‐spots within blood plasma fractions containing molecules within a narrow range of molecular weights.

Funder

Engineering and Physical Sciences Research Council

Horizon 2020 Framework Programme

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

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