<scp>Water‐soluble</scp> hyperbranched polymer with high curcumin content-Reference-Cited by-同舟云学术

Water‐soluble hyperbranched polymer with high curcumin content

Published:2023-09-06 Issue:46 Volume:140 Page:
ISSN:0021-8995
Container-title:Journal of Applied Polymer Science
language:en
Short-container-title:J of Applied Polymer Sci

Author:

Nakayama Yusuke¹,Ito Yutaro¹,Fukaminato Tsuyoshi¹,Xu Wei²,Niidome Takuro²,Kurihara Seiji¹,Kim Sunnam¹^ORCID

Affiliation:

1. Division of Materials Science and Chemistry, Faculty of Advanced Science and Technology Kumamoto University Kumamoto Japan

2. Division of Biomedical Engineering, Faculty of Advanced Science and Technology Kumamoto University Kumamoto Japan

Abstract

AbstractCurcumin is one of the promising anticancer drugs but has the problems of poor water solubility and rapid degradation in aqueous solution. In this study, a hyperbranched curcumin polymer having many carboxylic end groups is synthesized. The polymer is highly water‐soluble and contains a high amount of curcumins. Remarkable improvement of stability toward degradation and aggregation in aqueous solution is achieved. Its cellular uptake and cytotoxicity are also confirmed.

Funder

Japan Society for the Promotion of Science London

Ogasawara Foundation for the Promotion of Science and Engineering

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Surfaces, Coatings and Films,General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/app.54673

Reference34 articles.

1. Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts

2. Immunomodulation of Curcumin on Adoptive Therapy with T Cell Functional Imaging in Mice

3. The effect of Curcumin on multi-level immune checkpoint blockade and T cell dysfunction in head and neck cancer

4. Targeting regulatory T cells by curcumin: A potential for cancer immunotherapy

5. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

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