Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia
Author:
Affiliation:
1. Department of Leukemia; The University of Texas MD Anderson Cancer Center; Houston Texas
2. Department of Hematopathology; The University of Texas MD Anderson Cancer Center; Houston Texas
Funder
NIH/NCI
NCI
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ajh.24496/fullpdf
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4. STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells;Hazan-Halevy;Blood,2010
5. Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents;Turner;Semin Cancer Biol,2014
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