PMEPA1 interference activates PTEN / PI3K / AKT , thereby inhibiting the proliferation, invasion and migration of pancreatic cancer cells and enhancing the sensitivity to gemcitabine and cisplatin-Reference-Cited by-同舟云学术

PMEPA1 interference activates PTEN / PI3K / AKT , thereby inhibiting the proliferation, invasion and migration of pancreatic cancer cells and enhancing the sensitivity to gemcitabine and cisplatin

Published:2021-06-30 Issue:1 Volume:83 Page:64-74
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Development Research

Author:

Yang Yang¹²³,Cheng Tao⁴,Xie Peng⁵,Wang Lishan²³,Chen Hong⁵,Cheng Zhangjun²³,Zhou Jiahua¹²³^ORCID

Affiliation:

1. Nanjing Medical University Nanjing Jiangsu China

2. Department of Hepatic‐Biliary‐Pancreatic Center Zhongda Hospital of Southeast University Nanjing Jiangsu China

3. Department of Hepatobiliary Surgery Research Institute Southeast University Nanjing Jiangsu China

4. Department of General Surgery Zhongda Hospital of Southeast University Nanjing Jiangsu China

5. School of Medicine Southeast University Nanjing Jiangsu China

Publisher

Wiley

Subject

Drug Discovery

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21844

Reference30 articles.

1. TMEPAI/PMEPA1 inhibits Wnt signaling by regulating β-catenin stability and nuclear accumulation in triple negative breast cancer cells

2. Pancreatic cancer: yesterday, today and tomorrow

3. Dual inhibition of the PI3K and MAPK pathways enhances nab-paclitaxel/gemcitabine chemotherapy response in preclinical models of pancreatic cancer

4. Curcumin AntiCancer Studies in Pancreatic Cancer

5. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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