Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors

Author:

Hynds Robert E.12ORCID,Ben Aissa Assma3,Gowers Kate H.C.4,Watkins Thomas B.K.2,Bosshard-Carter Leticia14,Rowan Andrew J.2,Veeriah Selvaraju1,Wilson Gareth A.2,Quezada Sergio A.3,Swanton Charles12,Janes Sam M.4,

Affiliation:

1. UCL Cancer Institute, CRUK Lung Cancer Centre of Excellence; University College London; London United Kingdom

2. Translational Cancer Therapeutics Laboratory; The Francis Crick Institute; London United Kingdom

3. Cancer Immunology Unit; UCL Cancer Institute, University College London; London United Kingdom

4. Lungs for Living Research Centre, UCL Respiratory; University College London; London United Kingdom

Funder

Cancer Research UK

The CRUK Lung Cancer Centre of Excellence

Roy Castle Lung Cancer Foundation

Wellcome Trust

Stand Up To Cancer

Rosetrees Trust

NovoNordisk Foundation

Prostate Cancer Foundation

Breast Cancer Research Foundation

European Research Council

Marie Curie Network PloidyNet

National Institute for Health Research

The University College London Hospitals Biomedical Research Centre

The CRUK UCL Experimental Cancer Medicine Centre

Wellcome Trust Senior Fellow in Clinical Science

Francis Crick Institute

Medical Research Council

The Wellcome Trust

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference27 articles.

1. Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor;Chapman;J Clin Invest,2010

2. Efficient procurement of epithelial stem cells from human tissue specimens using a Rho-associated protein kinase inhibitor Y-27632. Tissue;Terunuma;Eng A,2010

3. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells;Rheinwatd;Cell,1975

4. Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens;Liu;Nat Protoc,2017

5. ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells;Liu;Am J Pathol,2012

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