Synergistic interaction between the agonism of cebranopadol at nociceptin/orphaninFQand classical opioid receptors in the rat spinal nerve ligation model-Reference-Cited by-同舟云学术

Synergistic interaction between the agonism of cebranopadol at nociceptin/orphaninFQand classical opioid receptors in the rat spinal nerve ligation model

Published:2018-11-28 Issue:6 Volume:6 Page:e00444
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Christoph Thomas¹^ORCID,Raffa Robert²³^ORCID,De Vry Jean⁴,Schröder Wolfgang⁵^ORCID

Affiliation:

1. Preclinical Drug Development Grünenthal GmbH Aachen Germany

2. Temple University School of Pharmacy Philadelphia Pennsylvania

3. University of Arizona College of Pharmacy Tucson Arizona

4. Grünenthal Innovation Grünenthal GmbH Aachen Germany

5. Translational Science and Intelligence Grünenthal GmbH Aachen Germany

Funder

Grünenthal GmbH

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.444

Reference33 articles.

1. Cebranopadol: a first in-class example of a nociceptin/orphanin FQ receptor and opioid receptor agonist

2. Cebranopadol: A Novel Potent Analgesic Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist

3. Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

4. Nociceptin/orphanin FQ opioid peptide (NOP) receptor and µ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain

5. Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel Opioids in the Setting of Acute Postoperative Pain: A Narrative Review;Pharmaceuticals;2023-12-25

2. Multitargeted Opioid Ligand Discovery as a Strategy to Retain Analgesia and Reduce Opioid-Related Adverse Effects;Journal of Medicinal Chemistry;2023-03-01

3. A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse;European Journal of Medicinal Chemistry;2022-12

4. PPL-138 (BU10038): A bifunctional NOP/mu partial agonist that reduces cocaine self-administration in rats;Neuropharmacology;2022-06

5. A Review on the Pain and Depression Comorbidity Animal Models;Korean Journal of Acupuncture;2021-06-27