Evaluation of Tetrahydropalmatine Enantiomers on the Activity of Five Cytochrome P450 Isozymes in Rats Using a Liquid Chromatography / Mass Spectrometric Method and a Cocktail Approach-Reference-Cited by-同舟云学术

Evaluation of Tetrahydropalmatine Enantiomers on the Activity of Five Cytochrome P450 Isozymes in Rats Using a Liquid Chromatography / Mass Spectrometric Method and a Cocktail Approach

Published:2015-06-02 Issue:8 Volume:27 Page:551-556
ISSN:0899-0042
Container-title:Chirality
language:en
Short-container-title:Chirality

Author:

Li Wuhong¹,Zhao Liang²,Le Jian³,Zhang Yinying¹²,Liu Yinli¹⁴,Zhang Guoqing²,Chai Yifeng¹⁴,Hong Zhanying¹⁴

Affiliation:

1. School of Pharmacy; Second Military Medical University; Shanghai China

2. Department of Pharmacy; Eastern Hepatobiliary Surgery Hospital; Shanghai China

3. Shanghai Institute for Food and Drug Control; Shanghai China

4. Shanghai Key Laboratory for Pharmaceutical Metabolite Research; Shanghai China

Funder

National Natural Scientific Foundation of China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference28 articles.

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2. Stereoselective pharmacokinetics of tetrahydropalmatine after oral administration of (-)-enantiomer and the racemate;Hong;Chirality,2005

3. Comparative studies on pharmacokinetic fates of tetrahydropalmatine enantiomers in different chemical environments in rats;Hong;Chirality,2008

4. Study on the stereoselective excretion of tetrahydropalmatine enantiomers in rats and identification of in vivo metabolites by liquid chromatography-tandem mass spectrometry;Hong;Chirality,2010

5. Progress in studies of the pharmacology of l-tetrahydropalmatine and l-stepholidine;Jin;Yao Xue Xue Bao,1987

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