Affiliation:
1. Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK
Abstract
AbstractPurposeTo develop a method for dynamic mapping and distortion correction.MethodsA blip‐rewound EPI trajectory was developed to acquire multiple 2D EPI images in a single readout with an interleaved order, which allows a short TE difference. A joint multi‐echo reconstruction was utilized to exploit the shared information between EPI images. The reconstructed images from each readout are combined to produce a final magnitude image. A map is calculated from the phase of these images for distortion correction. The efficacy of the proposed method is assessed with phantom and in vivo experiments. The performance of the proposed method in the presence of subject motion is also investigated.ResultsCompared to conventional multi‐echo EPI, the proposed method allows dynamic mapping at matched resolution with a much shorter TR. Phantom and in vivo results show that the proposed method can provide a comparable magnitude image as conventional single‐shot EPI. The maps calculated from the proposed method are consistent with conventional multi‐echo EPI in the phantom experiment. For in vivo experiments, the proposed method provides a more accurate estimation of than conventional multi‐echo EPI, which is prone to phase wrapping problems due to the long TE difference. In‐vivo scan with subject motion shows the proposed dynamic field mapping method can improve the temporal stability of EPI time series compared to gradient echo (GRE) based static field mapping.ConclusionThe proposed method allows accurate dynamic mapping for robust distortion correction without compromising spatial or temporal resolution.
Funder
Royal Academy of Engineering
NIHR Oxford Biomedical Research Centre
Wellcome Trust
Subject
Radiology, Nuclear Medicine and imaging