Adapting a practical EPR dosimetry protocol to measure output factors in small fields with alanine

Author:

Höfel Sebastian12ORCID,Liebig Pauline2,Fix Michael K.3,Drescher Malte1,Zwicker Felix245

Affiliation:

1. Department of Chemistry and Konstanz Research School Chemical Biology University of Konstanz Konstanz Germany

2. Klinik und Praxis für Strahlentherapie am Klinikum Konstanz Konstanz Germany

3. Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital Bern University Hospital and University of Bern Bern Switzerland

4. Department of Radiation Oncology Heidelberg University Hospital Heidelberg Germany

5. Clinical Cooperation Unit Molecular Radiation Oncology German Cancer Research Center (DKFZ) Heidelberg Germany

Abstract

AbstractPurposeModern radiotherapy techniques often deliver small radiation fields. In this work, a practical Electron Paramagnetic Resonance (EPR) dosimetry protocol is adapted and applied to measure output factors (OF) in small fields of a 6 MV radiotherapy system. Correction factors and uncertainties are presented and OFs are compared to the values obtained by following TRS‐483 using an ionization chamber (IC).MethodsIrradiations were performed at 10 cm depth inside a water phantom positioned at 90 cm source to surface distance with a 6 MV flattening filter free photon beam of a Halcyon radiotherapy system. OFs for different nominal field sizes (1 × 1, 2 × 2, 3 × 3, 4 × 4, normalized to 10 × 10 cm2) were determined with a PinPoint 3D (PTW 31022) IC following TRS‐483 as well as with alanine pellets with a diameter of 4 mm and a height of 2.4 mm. EPR readout was performed with a benchtop X‐band spectrometer. Correction factors due to volume averaging and due to positional uncertainties were derived from 2D film measurements.ResultsOFs obtained from both dosimeter types agreed within 0.7% after applying corrections for the volume averaging effect. For the used alanine pellets, volume averaging correction factors of 1.030(2) for the 1 × 1 cm2 field and <1.002 for the larger field sizes were determined. The correction factor for positional uncertainties of 1 mm was in the order of 1.018 for the 1 × 1 cm2 field. Combined relative standard uncertainties uc for the OFs resulting from alanine measurements were estimated to be below 1.5% for all field sizes. For IC measurements, uc was estimated to be below 1.0%.ConclusionsA practical EPR dosimetry protocol is adaptable for precisely measuring OFs in small fields down to 1 × 1 cm2. It is recommended to consider the effect of positional uncertainties for field sizes <2 × 2 cm2.

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging,Instrumentation,Radiation

Reference29 articles.

1. International Atomic Energy Agency.Dosimetry of small static fields used in external beam radiotherapy.Technical Report Series No. 483.International Atomic Energy Agency;2017:211

2. Deutsches Institut für Normung.2019. DIN 6809‐8. Clinical Dosimetry—Part 8: Dosimetry of small photon fields. doi:10.31030/3431259

3. Detector to detector corrections: A comprehensive experimental study of detector specific correction factors for beam output measurements for small radiotherapy beams

4. Dose measurements in small fields;Würfel JU;J Med Phys,2013

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