Model-Based Once-Daily Darunavir/Ritonavir Dosing Recommendations in Pediatric HIV-1-Infected Patients Aged≥3 to <12 Years
Author:
Affiliation:
1. Janssen Research & Development; Beerse Belgium
2. Janssen Research & Development; Titusville New Jersey USA
3. Janssen Infectious Diseases BVBA; Beerse Belgium
4. LAP&P Consultants BV; Leiden The Netherlands
Publisher
Wiley
Subject
Pharmacology (medical),Modeling and Simulation
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/psp4.44/fullpdf
Reference31 articles.
1. DHHS http://aidsinfo.nih.gov/contentfiles/lvguidelines/pediatricguidelines.pdf 2014
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3. Underdosing of antiretrovirals in UK and Irish children with HIV as an example of problems in prescribing medicines to children, 1997-2005: cohort study;Menson;BMJ,2006
4. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials;Clotet;Lancet,2007
5. Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: a randomized controlled phase III trial;Madruga;Lancet,2007
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