Synthesis of stable isotope-labelled firocoxib-Reference-Cited by-同舟云学术

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Synthesis of stable isotope-labelled firocoxib

Published:2020-05-05 Issue:8 Volume:63 Page:386-392
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Latli Bachir¹^ORCID,Gao Amy²,Kvaternick Valerie³,Tecle Berhane³,Pennino Scott²,Yee Nathan K.¹,Song Jeff¹

Affiliation:

1. Chemical Development; Boehringer Ingelheim Pharmaceuticals, Inc.; Ridgefield Connecticut USA

2. Material and Analytical Sciences; Boehringer Ingelheim Pharmaceuticals, Inc.; Ridgefield Connecticut USA

3. Boehringer Ingelheim Animal Health; North Brunswick New Jersey USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.3842/fullpdf

Reference16 articles.

1. Recent advancement in the discovery and development of COX-2 inhibitors: insight into biological activities and SAR studies (2008-2019);Sharma;Bioorg Chem,2019

2. Pharmacokinetics and metabolism of orally administered firocoxib, a novel second-generation coxib, in horses;Kvaternick;J Vet Pharmacol Therap,2007

3. A general, one-pot method for the synthesis of sulfinic acids from methyl sulfones;Guthier;Org Lett,2016

4. General and practical potassium methoxide/disilane-mediated dehalogenative deuteration of (hetero)arylhalides;Wang;J Am Chem Soc,2018

5. The dimethyl- d 6 firocoxib is available commercially

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