Rapid Determination of Vial Heat Transfer Parameters Using Tunable Diode Laser Absorption Spectroscopy (TDLAS) in Response to Step-Changes in Pressure Set-Point During Freeze-Drying

Author:

Kuu Wei Y.,Nail Steven L.,Sacha Gregory

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference16 articles.

1. Mass and heat transfer in vial freeze-drying of pharmaceuticals: Role of the vial;Pikal;J Pharm Sci,1984

2. The nonsteady state modeling of freeze drying: In-process product temperature and moisture content mapping and pharmaceutical product quality applications;Pikal;Pharm Dev Technol,2005

3. Determination of mass and heat transfer parameters during freeze-drying cycles of pharmaceutical products;Hottot;PDA J Pharmaceutical Sci Technol,2005

4. Evaluation of tunable diode laser absorption spectroscopy for in-process water vapor mass flux measurements during freeze drying;Gieseler;Journal of Pharmaceutical Sciences on-line publication,2007

5. Use of laboratory data in freeze drying process design: Heat and product resistance parameters and the compute simulation of freeze drying;Pikal;J Parenteral Sci. Tech,1985

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