Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype‐Derived Activity Scores-Reference-Cited by-同舟云学术

Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype‐Derived Activity Scores

Published:2020-11-03 Issue:12 Volume:9 Page:678-685
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Thomas Cameron D.¹,Mosley Scott A.¹,Kim Sarah²,Lingineni Karthik²,El Rouby Nihal¹,Langaee Taimour Y.¹,Gong Yan¹,Wang Danxin¹,Schmidt Siegfried O.³,Binkley Philip F.⁴,Estores David S.⁵,Feng Kairui⁶,Kim Hyewon⁶,Kinjo Minori⁶,Li Zhichuan⁶,Fang Lanyan⁶,Chapman Arlene B.⁷,Cooper-DeHoff Rhonda M.¹⁸,Gums John G.¹,Hamadeh Issam S.¹,Zhao Liang⁶,Schmidt Stephan²,Frye Reginald F.¹,Johnson Julie A.¹,Cavallari Larisa H.¹

Affiliation:

1. Department of Pharmacotherapy and Translation Research Center for Pharmacogenomics and Precision Medicine College of Pharmacy University of Florida Gainesville Florida USA

2. Department of Pharmaceutics Center for Pharmacometrics and Systems Pharmacology College of Pharmacy University of Florida Orlando Florida USA

3. Department of Community Health and Family Medicine College of Medicine University of Florida Gainesville Florida USA

4. Department of Cardiovascular Medicine College of Medicine The Ohio State University Columbus Ohio USA

5. Division of Gastroenterology, Hepatology & Nutrition College of Medicine University of Florida Gainesville Florida USA

6. Office of Research and Standards Office of Generic Drugs Center for Drug Evaluation and Research US Food and Drug Administration Silver Spring Maryland USA

7. Biological Sciences Division The University of Chicago Chicago Illinois USA

8. Division of Cardiovascular Medicine College of Medicine University of Florida Gainesville Florida USA

Funder

Food and Drug Administration

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12563

Reference36 articles.

1. The genetic polymorphism of debrisoquine/sparteine metabolism — Clinical aspects