Model‐Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes-Reference-Cited by-同舟云学术

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Model‐Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes

Published:2021-01-13 Issue:2 Volume:10 Page:108-118
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Jo Heeseung¹,Pilla Reddy Venkatesh¹²,Parkinson Joanna³,Boulton David W.⁴,Tang Weifeng⁴

Affiliation:

1. Modelling and Simulation, Early Oncology, Oncology R&D AstraZeneca Cambridge UK

2. Clinical Pharmacology and Quantitative Pharmacology BioPharmaceuticals R&D AstraZeneca Cambridge UK

3. Clinical Pharmacology and Quantitative Pharmacology, BioPharmaceuticals R&D AstraZeneca Gothenburg Sweden

4. Clinical Pharmacology and Quantitative Pharmacology, BioPharmaceuticals R&D AstraZeneca Gaithersburg Maryland USA

Funder

AstraZeneca

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12577

Reference32 articles.

1. Dapagliflozin: A Review of Its Use in Patients with Type 2 Diabetes

2. Pharmaceutical approval update;Goldenberg M.M.;P & T.,2014

3. Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

4. Simultaneous oral therapeutic and intravenous14C-microdoses to determine the absolute oral bioavailability of saxagliptin and dapagliflozin

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