Pathological mechanisms underlying single large-scale mitochondrial DNA deletions

Author:

Rocha Mariana C.1,Rosa Hannah S.1,Grady John P.1,Blakely Emma L.12,He Langping12,Romain Nadine34,Haller Ronald G.34,Newman Jane1,McFarland Robert1,Ng Yi Shiau1,Gorman Grainne S.1,Schaefer Andrew M.1,Tuppen Helen A.1,Taylor Robert W.12,Turnbull Doug M.1

Affiliation:

1. Wellcome Centre for Mitochondrial Research, Institute of Neuroscience; Newcastle University; Newcastle upon Tyne United Kingdom

2. National Health Service Highly Specialised Mitochondrial Diagnostic Laboratory, Newcastle upon Tyne Hospitals; National Health Service Foundation Trust; Newcastle upon Tyne United Kingdom

3. Department of Neurology and Neurotherapeutics; University of Texas Southwestern Medical Center; Dallas TX

4. Institute for Exercise and Environmental Medicine of Texas Health Presbyterian Hospital; Dallas TX.

Funder

Wellcome Centre for Mitochondrial Research

Medical Research Council

Newcastle University Centre for Ageing and Vitality

Biotechnology and Biological Sciences Research Council

Mitochondrial Disease Patient Cohort

Lily Foundation

National Institute for Health Research Biomedical Research Centre for Ageing and Age-Related Disease

NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children

National Institutes of Health

NIHR Biomedical Research Centre for Ageing and Age-related disease

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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