Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds
Author:
Affiliation:
1. Department of Molecular Biochemistry; Faculty of Chemistry, University of Gdansk, ul. Wita Stwosza 63; Gdansk 80-308 Poland
2. Pharmaceutical Institute, University of Bonn, An der Immenburg 4; Bonn 53121 Germany
Funder
National Science Centre
German Research Foundation
Publisher
Wiley
Subject
Organic Chemistry,Biomaterials,Biochemistry,General Medicine,Biophysics
Reference65 articles.
1. Twenty years of theMEROPSdatabase of proteolytic enzymes, their substrates and inhibitors
2. Type II transmembrane serine proteases in development and disease
3. Matriptase-2, a Membrane-bound Mosaic Serine Proteinase Predominantly Expressed in Human Liver and Showing Degrading Activity against Extracellular Matrix Proteins
4. Matriptase-2 Inhibits Breast Tumor Growth and Invasion and Correlates with Favorable Prognosis for Breast Cancer Patients
5. Genetic upregulation of matriptase‐2 reduces the aggressiveness of prostate cancer cells in vitro and in vivo and affects FAK and paxillin localisation
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Cyclic Peptidic Furin Inhibitors Developed by Combinatorial Chemistry;ACS Medicinal Chemistry Letters;2023-03-15
2. Diarylethene‐Based Photoswitchable Inhibitors of Serine Proteases;Angewandte Chemie International Edition;2021-08-25
3. Diarylethen‐basierte lichtschaltbare Inhibitoren von Serinproteasen;Angewandte Chemie;2021-08-24
4. Bowman-Birk Inhibitors: Insights into Family of Multifunctional Proteins and Peptides with Potential Therapeutical Applications;Pharmaceuticals;2020-11-25
5. The ectodomain of matriptase-2 plays an important nonproteolytic role in suppressing hepcidin expression in mice;Blood;2020-08-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3