Candida albicans cholecystitis in a dog with diabetes mellitus

Author:

Verwey Elize1ORCID,Weltan Sandra Mary23,Whitehead Zandri14ORCID

Affiliation:

1. Internal Medicine Clinic Tygerberg Animal Hospital Cape Town South Africa

2. Vetdiagnostix Veterinary Pathology Services Cape Town South Africa

3. Gribbles Veterinary Palmerston North New Zealand

4. Internal Medicine Service Adelaide Veterinary Specialist and Referral Centre Adelaide Australia

Abstract

AbstractA 10‐year‐old, 8.9‐kg, spayed, female Jack Russell Terrier, with previously well‐controlled diabetes mellitus, presented with hyporexia of 2‐day duration. Cranial abdominal pain and weight loss were detected on clinical examination. Blood tests, urinalysis, urine protein:creatinine ratio, blood pressure, abdominal ultrasound and liver aspirate cytology revealed hyperglycaemia, elevated serum liver enzyme activities, glucosuria, proteinuria, hypertension, rounded liver edges, irregular hyperechoic gall bladder wall thickening, irregular hyperechoic gall bladder content and vacuolar hepatopathy. Bile cytological examination demonstrated fungal organisms, which were identified as Candida albicans on bile fungal culture. No bacteria were detected on bile cytological examination or bile bacterial aerobic and anaerobic culture. The dog was diagnosed with Candida albicans cholecystitis and recovered after a 12‐week course of oral ketoconazole. This case report highlights the value of performing bile cytology in suspect canine cholecystitis cases and is the first to describe Candida albicans fungal cholecystitis without bacterial coinfection in dogs.

Publisher

Wiley

Subject

General Veterinary

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