Development of a mass spectrometry based detection method for the mitochondrion-derived peptide MOTS-c in plasma samples for doping control purposes
Author:
Affiliation:
1. Center for Preventive Doping Research, German Sport University Cologne,; Institute of Biochemistry; Am Sportpark Müngersdorf 6 50933 Cologne Germany
2. European Monitoring Center for Emerging Doping Agents (EuMoCEDA); Cologne/Bonn Germany
Funder
Federal Ministry of the Interior - Federal Republic of Germany
Manfred-Donike Institute for Doping Analysis
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Analytical Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/rcm.8337/fullpdf
Reference23 articles.
1. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance;Lee;Cell Metab,2015
2. AMPK--sensing energy while talking to other signaling pathways;Hardie;Cell Metab,2014
3. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha;Jäger;Proc Natl Acad Sci U S A,2007
4. Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation;Ming;Biochem Biophys Res Commun,2016
5. Mitochondrially derived peptides as novel regulators of metabolism;Kim;J Physiol,2017
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1. From whence it came: Mitochondrial mRNA leaves, a protein returns;Cell Metabolism;2024-07
2. MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study;International Journal of Molecular Sciences;2023-10-06
3. Stability Determination of Intact Humanin-G with Characterizations of Oxidation and Dimerization Patterns;Biomolecules;2023-03-11
4. Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging;Journal of Translational Medicine;2023-01-20
5. Circulating levels of MOTS-c in patients with breast cancer treated with metformin;Aging;2022-12-06
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