Oncolytic vaccinia virus demonstrates antiangiogenic effects mediated by targeting of VEGF

Author:

Hou Weizhou1,Chen Hannah1,Rojas Juan1,Sampath Padma1,H. Thorne Stephen1

Affiliation:

1. Department of Surgery; University of Pittsburgh Cancer Institute, University of Pittsburgh; PA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference27 articles.

1. Oncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses;Guo;Biochim Biophys Acta,2008

2. Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer;Kirn;Nat Rev Cancer,2009

3. Amgen spikes interest in live virus vaccines for hard-to-treat cancers;Schmidt;Nat Biotechnol,2011

4. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans;Breitbach;Nature,2011

5. Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial;Park;Lancet Oncol,2008

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