A comparison of DNA sequencing and gene expression profiling to assist tissue of origin diagnosis in cancer of unknown primary

Author:

Posner Atara1ORCID,Prall Owen WJ2,Sivakumaran Tharani34,Etemadamoghadam Dariush5,Thio Niko5,Pattison Andrew1,Balachander Shiva1,Fisher Krista5,Webb Samantha5,Wood Colin5,DeFazio Anna678,Wilcken Nicholas9,Gao Bo9,Karapetis Christos S10,Singh Madhu11,Collins Ian M12,Richardson Gary13,Steer Christopher14,Warren Mark15,Karanth Narayan16,Wright Gavin17,Williams Scott18,George Joshy19,Hicks Rodney J20,Boussioutas Alex21,Gill Anthony J22,Solomon Benjamin J3,Xu Huiling2,Fellowes Andrew2,Fox Stephen B24,Schofield Penelope42324,Bowtell David45,Mileshkin Linda34,Tothill Richard W14ORCID

Affiliation:

1. Department of Clinical Pathology and Centre for Cancer Research University of Melbourne Melbourne VIC Australia

2. Department of Pathology Peter MacCallum Cancer Centre Melbourne VIC Australia

3. Department of Medical Oncology Peter MacCallum Cancer Centre Melbourne VIC Australia

4. Sir Peter MacCallum Department of Oncology University of Melbourne Melbourne VIC Australia

5. Peter MacCallum Cancer Centre Melbourne VIC Australia

6. The Westmead Institute for Medical Research Sydney NSW Australia

7. Department of Gynaecological Oncology Westmead Hospital Sydney NSW Australia

8. The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW Sydney NSW Australia

9. Department of Medical Oncology Crown Princess Mary Cancer Centre, Westmead Hospital Sydney NSW Australia

10. Department of Medical Oncology Flinders University and Flinders Medical Centre Adelaide SA Australia

11. Department of Medical Oncology Barwon Health Cancer Services Geelong VIC Australia

12. Department of Medical Oncology, SouthWest HealthCare Warrnambool and Deakin University Geelong VIC Australia

13. Department of Medical Oncology Cabrini Health Melbourne VIC Australia

14. Border Medical Oncology Albury Wodonga Regional Cancer Centre Albury NSW Australia

15. Department of Medical Oncology Bendigo Health Bendigo VIC Australia

16. Division of Medicine Alan Walker Cancer Centre Darwin NT Australia

17. Department of Cardiothoracic Surgery St Vincent's Hospital Melbourne VIC Australia

18. Department of Radiation Oncology Peter MacCallum Cancer Centre Melbourne VIC Australia

19. Department of Computational Sciences The Jackson Laboratory Farmington Connecticut USA

20. The St Vincent's Hospital Department of Medicine University of Melbourne Melbourne VIC Australia

21. Department of Medicine, Royal Melbourne Hospital University of Melbourne Melbourne VIC Australia

22. Cancer Diagnosis and Pathology Group, Kolling Institute of Medical, Research and Sydney Medical School University of Sydney Sydney NSW Australia

23. Department of Psychology, and Iverson Health Innovation Research Institute Swinburne University Melbourne VIC Australia

24. Behavioural Sciences Unit, Health Services Research and Implementation Sciences Peter MacCallum Cancer Centre Melbourne VIC Australia

Funder

Cancer Australia

Cancer Institute NSW

Victorian Cancer Agency

American Association for Cancer Research

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference63 articles.

1. Cancer of unknown primary site

2. The currently declining incidence of cancer of unknown primary

3. Cancer data in Australia;Australian Institute for Health and Welfare;Australian Cancer Incidence and Mortality (ACIM) books: cancer of unknown primary site,2019

4. Carcinomas of an unknown primary origin—diagnosis and treatment

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