Optimizing subgroup selection in two‐stage adaptive enrichment and umbrella designs-Reference-Cited by-同舟云学术

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Optimizing subgroup selection in two‐stage adaptive enrichment and umbrella designs

Published:2021-03-29 Issue: Volume: Page:
ISSN:0277-6715
Container-title:Statistics in Medicine
language:en
Short-container-title:Statistics in Medicine

Author:

Ballarini Nicolás M.¹^ORCID,Burnett Thomas²^ORCID,Jaki Thomas²³^ORCID,Jennison Christoper⁴^ORCID,König Franz¹^ORCID,Posch Martin¹^ORCID

Affiliation:

1. Section for Medical Statistics Medical University of Vienna Vienna Austria

2. Department of Mathematics and Statistics Lancaster University Lancaster UK

3. MRC Biostatistics Unit University of Cambridge Cambridge UK

4. Department of Mathematical Sciences University of Bath Bath UK

Funder

H2020 Marie Skłodowska-Curie Actions

Innovative Medicines Initiative

Medical Research Council Canada

National Institute for Health Research

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.8949

Reference52 articles.

1. General guidance on exploratory and confirmatory subgroup analysis in late-stage clinical trials

2. Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials

3. Methods for identification and confirmation of targeted subgroups in clinical trials: A systematic review

4. Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

5. Clinical Trial Designs for Predictive Biomarker Validation: Theoretical Considerations and Practical Challenges

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4. How therapeutic advances have transformed the medical landscape: a primer for clinicians;Internal Medicine Journal;2023-06-23

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