A validated UPLC–MS/MS method for quantitative determination of a potent neuroprotective agent Sarsasapogenin‐AA13 in rat plasma: Application to pharmacokinetic studies-Reference-Cited by-同舟云学术

A validated UPLC–MS/MS method for quantitative determination of a potent neuroprotective agent Sarsasapogenin‐AA13 in rat plasma: Application to pharmacokinetic studies

Published:2020-01-17 Issue:3 Volume:34 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Pei Lixia¹^ORCID,Ye Yiyi¹,Zhao Wenshu¹,Ye Qun¹,Ge Songlan¹,Jiang Zi‐wei¹,Liang Xiao‐qiang¹,Gan Hai‐xian²,Ma Lei²

Affiliation:

1. Longhua HospitalShanghai University of Traditional Chinese Medicine Shanghai China

2. School of PharmacyEast China University of Science and Technology Shanghai China

Funder

Science and Technology Innovation Project of Longhua Hospital

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4775

Reference18 articles.

1. Sarsasapogenin-AA13 inhibits LPS-induced inflammatory responses in macrophage cells in vitro and relieves dimethylbenzene-induced ear edema in mice

2. Sarsasapogenin reverses depressive-like behaviors and nicotinic acetylcholine receptors induced by olfactory bulbectomy

3. Stereoisomerism metabolites found in rats after oral administration of timosaponin B-II using HPLC-Q-TOF-MS and NMR methods

4. Concise synthesis and antitumor activities of trisaccharide steroidal saponins

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