Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo

Author:

Thom Tobias1,Schmitz Matthias1ORCID,Fischer Anna‐Lisa1,Correia Angela1,Correia Susana1,Llorens Franc123,Pique Anna‐Villar123,Möbius Wiebke4,Domingues Renato5,Zafar Saima16,Stoops Erik7,Silva Christopher J.8,Fischer Andre91011,Outeiro Tiago F.51213,Zerr Inga1

Affiliation:

1. Department of Neurology University Medical Center Göttingen and the German Center for Neurodegenerative Diseases Göttingen Germany

2. Network Center for Biomedical Research of Neurodegenerative Diseases (CIBERNED) Institute Carlos III Madrid Spain

3. Bellvitge Biomedical Research Institute L'Hospitalet de Llobregat Spain

4. Department for Neurogenetics EM Core Unit Max Planck Institute for Experimental Medicine Göttingen Germany

5. Department of Experimental Neurodegeneration University Medical Center Göttingen Göttingen Germany

6. Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering National University of Sciences and Technology Islamabad Pakistan

7. ADx NeuroSciences Ghent Belgium

8. Produce Safety & Microbiology Research Unit, Western Regional Research Center, United States Department of Agriculture Agricultural Research Service Albany California USA

9. Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases German Center for Neurodegenerative Diseases Göttingen Germany

10. Department of Psychiatry and Psychotherapy University Medical Center Göttingen Göttingen Germany

11. Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC) University of Göttingen Göttingen Germany

12. Max Planck Institute for Experimental Medicine Goettingen Germany

13. Translational and Clinical Research Institute, Faculty of Medical Sciences Newcastle University Newcastle Upon Tyne United Kingdom

Funder

Alzheimer's Drug Discovery Foundation

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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