Atropisomeric property of 1-(2,6-difluorobenzyl)-3-[(2R)-amino-2-phenethyl]-5-(2-fluoro-3-methoxyphenyl)-6-methyluracil

Author:

Tucci Fabio C.,Hu Tao,Mesleh Michael F.,Bokser Allan,Allsopp Eric,Gross Timothy D.,Guo Zhiqiang,Zhu Yun-Fei,Struthers R. Scott,Ling Nicholas,Chen Chen

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference24 articles.

1. (a) . Stereochemistry of organic compounds. New York: John Wiley & Sons, Inc.; 1994. p 1120-1121.

2. Atropisomerism, biphenyls and the Suzuki coupling: peptide antibiotics

3. Binapthyls as chiral elements for asymmetric synthesis. In: editor. Stereocontrolled organic synthesis. Oxford: Blackwell; 1994. p 1-15.

4. In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)-one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites

5. Enantiomerization of an atropisomeric drug

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