Immunomodulation in Middle-Aged Humans Via the Ingestion of Physta® Standardized Root Water Extract of Eurycoma longifolia Jack-A Randomized, Double-Blind, Placebo-Controlled, Parallel Study

Author:

George Annie1,Suzuki Naoko2,Abas Azreena Binti1,Mohri Kiminori3,Utsuyama Masanori45,Hirokawa Katsuiku45,Takara Tsuyoshi6

Affiliation:

1. Research and Development Department; Biotropics Malaysia Berhad; Lot 21, Jalan U1/19 Section U1, Hicom-Glenmarie Industrial Park 40150 Shah Alam Selangor Malaysia

2. Research and Development Department, ORTHOMEDICO Inc.; Tokyo Medical & Dental University M&D Tower 25F; 1-5-45, Yushima Bunkyo Tokyo 113-8519 Japan

3. Meiji Pharmaceutical University; 2-522-1 Noshio Kiyose Tokyo 204-8588 Japan

4. Graduate School of Medical and Dental Sciences; Tokyo Medical and Dental University; 1-5-45 Yushima Bunkyo Tokyo 113-8519 Japan

5. Institute for Health and Life Science Co., Ltd.; Tokyo Medical and Dental University Open Laboratory, Medical Research Institute; Surugadai Bldg, 2-3-10, Surugadai, Kanda Chiyoda Tokyo 101-0062 Japan

6. Seishinkai Medical Association Inc.; Takara Medical Clinic; Taisei Bldg 9F, 2-3-2, Higashi-Gotanda Shinagawa Tokyo 141-0022 Japan

Funder

NKEA Research Grant Scheme

Publisher

Wiley

Subject

Pharmacology

Reference34 articles.

1. Determination of bioactive peptide (4.3 kDa) as an aphrodisiac marker in six Malaysian plants;Asiah;J Trop Forest Sci,2007

2. Tongkat ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance;Bhat;Fitoterapia,2010

3. Impact of DHEA(S) and cortisol on immune function in aging: a brief review;Buford;Appl Physiol Nutr Metab,2008

4. Age-related decline in RACK-1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone;Corsini;J Leukoc Biol,2005

5. The immunomodulating effect by ingestion of an Echinacea purprea preparation;Fujii;Pharmacometrics,2011

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