Fe II Metallohelices Stabilize DNA G‐Quadruplexes and Downregulate the Expression of G‐Quadruplex‐Regulated Oncogenes
Author:
Affiliation:
1. Institute of Biophysics Czech Academy of Sciences Kralovopolska 135 61265 Brno Czech Republic
2. Department of Chemistry University of Warwick Coventry CV4 7AL UK
Funder
Grantová Agentura České Republiky
Publisher
Wiley
Subject
General Chemistry,Catalysis,Organic Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202101388
Reference65 articles.
1. The Structure and Function of DNA G-Quadruplexes
2.
3. Quantitative visualization of DNA G-quadruplex structures in human cells
4. Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy
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1. Metallohelices stabilize DNA three-way junctions and induce DNA damage in cancer cells;Nucleic Acids Research;2023-06-23
2. Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-04-05
3. Bioinorganic supramolecular coordination complexes and their biomedical applications;FEBS Letters;2022-11-17
4. Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles;Nucleic Acids Research;2022-01-08
5. Dinuclear nickel(ii) supramolecular helicates down-regulate gene expression in human cells by stabilizing DNA G-quadruplexes formed in the promoter regions;Inorganic Chemistry Frontiers;2022
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