Unveiling the Potential of Innovative Gold(I) and Silver(I) Selenourea Complexes as Anticancer Agents Targeting TrxR and Cellular Redox Homeostasis-Reference-Cited by-同舟云学术

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Unveiling the Potential of Innovative Gold(I) and Silver(I) Selenourea Complexes as Anticancer Agents Targeting TrxR and Cellular Redox Homeostasis

Published:2022-10-25 Issue:70 Volume:28 Page:
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chemistry A European J

Author:

De Franco Michele¹,Saab Marina²,Porchia Marina³,Marzano Cristina¹,Nolan Steven P.²,Nahra Fady²⁴,Van Hecke Kristof²,Gandin Valentina¹^ORCID

Affiliation:

1. Dipartimento di Scienze del Farmaco Università degli Studi di Padova Via F. Marzolo 5 I-35131 Padova Italy

2. Department of Chemistry Center for Sustainable Chemistry Ghent University Krigsman 281, Building S3 9000 Ghent Belgium

3. ICMATE-CNR Corso Stati Uniti 4 I-35131 Padova Italy

4. VITO (Flemish Institute for Technological Research) Boeretang 200 2400 Mol Belgium

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Universitair Ziekenhuis Gent

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202201898

Reference49 articles.

1. Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions

2. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.

3. Metal- and Semimetal-Containing Inhibitors of Thioredoxin Reductase as Anticancer Agents

4. The Thioredoxin System: A Promising Target for Cancer Drug Development

5. A focus on the biological targets for coinage metal-NHCs as potential anticancer complexes

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1. Modular Synthesis of Azines Bearing a Guanidine Core from N‐Heterocyclic Carbene (NHC)‐Derived Selenoureas and Diazo Reagents;Chemistry – A European Journal;2024-09-03

2. A review on the recent advances of interaction studies of anticancer metal-based drugs with therapeutic targets, DNA and RNAs;Drug Discovery Today;2024-07

3. First Generation of Antioxidant Precursors for Bioisosteric Se-NSAIDs: Design, Synthesis, and In Vitro and In Vivo Anticancer Evaluation;Antioxidants;2023-08-24

4. Novel Silver Complexes Based on Phosphanes and Ester Derivatives of Bis(pyrazol-1-yl)acetate Ligands Targeting TrxR: New Promising Chemotherapeutic Tools Relevant to SCLC Management;International Journal of Molecular Sciences;2023-02-17

5. Organic selenocompounds: are they the panacea for human illnesses?;New Journal of Chemistry;2023

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