Affiliation:
1. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education School of Foreign Languages College of Chemistry & Materials Science Northwest University 710069 Xi'an P. R. China
Abstract
AbstractBulk chemical 2‐methyl‐2‐butene, one of the main C5 distillates of the petrochemical industry, has scarcely been utilized directly in synthesizing high‐value‐added fine chemicals. Herein, we use 2‐methyl‐2‐butene as the starting material to develop a palladium‐catalyzed highly site‐ and regio‐selective C‐3 dehydrogenation reverse prenylation of indoles. This synthetic method features mild reaction conditions, a broad substrate scope, atom‐ and step‐economies.
Funder
National Natural Science Foundation of China
Subject
General Chemistry,Catalysis,Organic Chemistry