A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs**-Reference-Cited by-同舟云学术

A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs**

Published:2020-11-03 Issue:70 Volume:26 Page:16818-16823
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Hayhow Thomas G.¹^ORCID,Borrows Rachel E. A.¹,Diène Coura R.¹,Fairley Gary²^ORCID,Fallan Charlene¹^ORCID,Fillery Shaun M.¹^ORCID,Scott James S.¹^ORCID,Watson David W.¹

Affiliation:

1. Medicinal Chemistry, Oncology R&D, Research and Early Development AstraZeneca Cambridge Science Park, Unit 310 Darwin Building Cambridge CB4 0WG UK

2. Medicinal Chemistry, Oncology R&D, Research and Early Development AstraZeneca Macclesfield Campus, Etherow Building, Silk Road Industrial Estate Macclesfield SK10 2NA UK

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202003137

Reference44 articles.

1. Thalidomide: The Tragedy of Birth Defects and the Effective Treatment of Disease

2. Teratogenic effects of thalidomide: molecular mechanisms

3. Thalidomide in the treatment of lepra reactions

5. Thalidomide a promising new treatment for rheumatoid arthritis

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis, and biological evaluation of RSL3-based GPX4 degraders with hydrophobic tags;European Journal of Medicinal Chemistry;2024-11

2. A one-pot photocatalytic triazole-based linkerology for PROTACs;Cell Reports Physical Science;2024-08

3. Structural and Physicochemical Features of Oral PROTACs;Journal of Medicinal Chemistry;2024-07-30

4. Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer;Journal of Medicinal Chemistry;2024-07-11

5. Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer;Journal of Medicinal Chemistry;2024-03-26