Bowl‐Shaped Kekulene Analogues: Cycloarenes with two Five‐Membered Rings

Author:

Murakami Hideyuki1,Iwabuchi Hiroki1,Asari Miki1,Yamada Hiroko2ORCID,Kuzuhara Daiki1ORCID

Affiliation:

1. Department of Physical Science and Materials Engineering Iwate University 4-3-5 Ueda Morioka 020-8551 Japan

2. Institute for Chemical Research Kyoto University Uji Kyoto 611-0011 Japan

Abstract

AbstractKekulene, a cycloarene composed of 12 fused benzene rings in a circular arrangement, exhibits a highly planar and robust structure. Kekulene has been the subject of investigation into its aromaticity and electronic structure, particularly in relation to the cyclic benzenoid. We have successfully synthesized novel bowl‐shaped kekulene analogues with five‐membered rings incorporated into the kekulene structure. The results of DFT calculations and VT‐NMR spectra indicate that inversion of their concave‐convex structures occurs at room temperature. The NICS and AICD plots predict that the Clar's type resonance structure is found in a manner analogous to the pristine kekulene, albeit with the interruption of the π‐conjugation on the sp3 carbons at the five‐membered rings. Despite the presence of the Clar's resonance structure, the Diels‐Alder reaction proceeded smoothly with a dienophile, in contrast to the behavior of planar kekulene derivatives. This study will lead to the creation of novel bowl‐shaped compounds and development of reactivity in aromatic compounds.

Publisher

Wiley

Reference44 articles.

1. Cycloarenes, a New Class of Aromatic Compounds, I. Synthesis of Kekulene

2. The Diamagnetic Anisotropy of Large Aromatic Systems: III Structures with Hexagonal Symmetry

3. E. Clar The Aromatic Sextet John Wiley and Sons London.1972.

4. E. V. Anslyn D. A. Dougherty in Modern Physical Organic Chemistry ed. J. Murdzek University Science Books. United States 2006 1 20–22.

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