Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PL pro-Reference-Cited by-同舟云学术

Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PL pro

Published:2021-11-23 Issue:71 Volume:27 Page:17928-17940
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chemistry A European J

Author:

Gil‐Moles Maria¹,Türck Sebastian¹,Basu Uttara¹^ORCID,Pettenuzzo Andrea²^ORCID,Bhattacharya Saurav³^ORCID,Rajan Ananthu³^ORCID,Ma Xiang³,Büssing Rolf¹,Wölker Jessica¹,Burmeister Hilke¹,Hoffmeister Henrik¹,Schneeberg Pia¹,Prause Andre¹,Lippmann Petra¹,Kusi‐Nimarko Josephine⁴,Hassell‐Hart Storm⁴,McGown Andrew⁴,Guest Daniel⁴,Lin Yan⁵^ORCID,Notaro Anna⁵,Vinck Robin⁵^ORCID,Karges Johannes⁵^ORCID,Cariou Kevin⁵^ORCID,Peng Kun⁶^ORCID,Qin Xue⁷,Wang Xing⁷,Skiba Joanna⁸^ORCID,Szczupak Łukasz⁸^ORCID,Kowalski Konrad⁸^ORCID,Schatzschneider Ulrich⁶,Hemmert Catherine⁷^ORCID,Gornitzka Heinz⁷^ORCID,Milaeva Elena R.⁹^ORCID,Nazarov Alexey A.⁹^ORCID,Gasser Gilles⁵^ORCID,Spencer John⁴^ORCID,Ronconi Luca²^ORCID,Kortz Ulrich³^ORCID,Cinatl Jindrich¹⁰,Bojkova Denisa¹⁰,Ott Ingo¹^ORCID

Affiliation:

1. Institute of Medicinal and Pharmaceutical Chemistry Technische Universität Braunschweig Beethovenstr. 55 38106 Braunschweig Germany

2. School of Chemistry National University of Ireland Galway University Road H91 TK33 Galway Ireland

3. Department of Life Sciences and Chemistry Jacobs University Campus Ring 1 28759 Bremen Germany

4. Department of Chemistry School of Life Sciences University of Sussex Falmer BN1 9QJ Brighton East Sussex UK

5. Chimie ParisTech PSL University CNRS Institute of Chemistry for Life and Health Sciences Laboratory for Inorganic Chemical Biology 75005 Paris France

6. Institut für Anorganische Chemie Julius-Maximilians-Universität Würzburg Am Hubland 97074 Würzburg Germany

7. LCC–CNRS Université de Toulouse CNRS UPS Toulouse France

8. Faculty of Chemistry Department of Organic Chemistry University of Łódź Tamka 12 91-403 Łódź Poland

9. Department of Medicinal Chemistry and Fine Organic Synthesis Lomonosov Moscow State University Leninskie Gory 1/3 119991 Moscow Russia

10. Institute of Medical Virology Universitätsklinikum Frankfurt Paul-Ehrlich-Str. 40 60596 Frankfurt Germany

Funder

Deutsche Forschungsgemeinschaft

Russian Foundation for Basic Research

Niedersächsisches Ministerium für Wissenschaft und Kultur

European Research Council

Engineering and Physical Sciences Research Council

Niemann-Pick Research Foundation