Affiliation:
1. School of Food and Biological Engineering Anhui Province Key Laboratory of Advance Catalytic Materials and Reaction Engineering Hefei University of Technology Hefei 230009 P. R. China
Abstract
AbstractA novel visible‐light photoredox strategy is reported for the efficient dehydroxylative alkylation of a wide array of α‐hydroxy carboxylic acid derivatives using diaryl boron radical. The reaction features readily accessible starting materials, broad substrate scope with excellent functionality tolerance. Preliminary mechanistic studies reveal that the spin‐center shift process is responsible for the C−O bond activation, which is promoted by the diaryl boron radical generated from bench‐stable and commercially available tetraphenyl borate (NaBPh4).
Funder
National Natural Science Foundation of China
National Key Research and Development Program of China
Fundamental Research Funds for the Central Universities
Subject
General Chemistry,Catalysis,Organic Chemistry