Affiliation:
1. Laboratorium für Organische Chemie ETH Zürich Vladimir-Prelog-Weg 3 8093 Zürich Switzerland
Abstract
AbstractGiven the prevalence of molecules containing nitro groups in organic synthesis, innovative methods to expand the reactivity of this functional group are of interest in both industrial and academic settings. In this report, a metal‐free intramolecular benzylic sp3 C−H amination is disclosed using aryl nitro compounds as aryl nitrene precursors. Organosilicon reagent N,N’‐bis(trimethylsilyl)‐4,4’‐bipyridinylidene (Si‐DHBP) served as an efficient reductant in the transformation, enabling the in situ generation of aryl nitrene species for the direct, metal‐free synthesis of unprotected 2‐arylindolines from the corresponding nitroarene compounds.
Funder
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Eidgenössische Technische Hochschule Zürich
Subject
General Chemistry,Catalysis,Organic Chemistry
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献