Recent Progress in the Synthesis of Silaspiranes

Author:

Chen Hua1,Hu Xuejiao1,Wang Wanshu23,Gao Lu2,Song Zhenlei2ORCID

Affiliation:

1. College of Pharmaceutical Science and Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals Zhejiang University of Technology 310014 Hangzhou P. R. China

2. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology West China School of Pharmacy Sichuan University 610064 Chengdu P. R. China

3. Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education Hangzhou Normal University 311121 Hangzhou P. R. China

Abstract

AbstractSilaspiranes bearing a spiro‐silicon center are promising ring frameworks for the synthesis of novel spirocyclic molecules possessing unique properties. Development of efficient methods towards these ring structures has therefore attracted considerable attentions of synthetic chemists. This minireview highlights the representative advances in the field, and is categorized into four parts according to the ring formation strategies: cyclization, annulation, ring expansion and cycloaddition.

Funder

National Natural Science Foundation of China

Science and Technology Department of Sichuan Province

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

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