Affiliation:
1. Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama University 1-1-1 Tsushima-naka, Kita-ku Okayama 7008530 Japan
Abstract
AbstractIn this work, a straightforward synthesis of C3−N1’ bisindolines is achieved by a formal umpolung strategy. The protocols were tolerant of a wide variety of substituents on the indole and indoline ring. In addition, the C3−N1’ bisindolines could be converted to C3−N1’ indole‐indolines and C3−N1’‐bisindoles. Also, we have successfully synthesized (±)‐rivularin A through a biomimetic late‐stage tribromination as a key step.
Subject
General Chemistry,Catalysis,Organic Chemistry