Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity

Author:

Vrettos Eirinaios I.1ORCID,Valverde Ibai E.23ORCID,Mascarin Alba2,Pallier Patrick N.4ORCID,Cerofolini Linda5,Fragai Marco65ORCID,Parigi Giacomo65ORCID,Hirmiz Baydaa7,Bekas Nick1,Grob Nathalie M.8ORCID,Stylos Evgenios Κ.1ORCID,Shaye Hamidreza9,Del Borgo Mark7,Aguilar Marie‐Isabel7,Magnani Francesca10,Syed Nelofer11,Crook Timothy12ORCID,Waqif Emal4,Ghazaly Essam13,Cherezov Vadim9ORCID,Widdop Robert E.14ORCID,Luchinat Claudio65ORCID,Michael‐Titus Adina T.4ORCID,Mindt Thomas L.2151617,Tzakos Andreas G.1ORCID

Affiliation:

1. Department of Chemistry University of Ioannina Ioannina 45110 Greece

2. Division of Radiopharmaceutical Chemistry University of Basel Hospital Petersgraben 4 4031 Basel Switzerland

3. Institut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB), UMR 6302 CNRS Université de Bourgogne Franche-Comté 9 Avenue Alain Savary 21000 Dijon France

4. Centre for Neuroscience and Trauma, The Blizard Institute, Barts and The London School of Medicine and Dentistry Queen Mary, University of London 4 Newark Street, Whitechapel London E1 2AT UK

5. Consorzio Interuniversitario Risonanze Magnetiche MetalloProteine, (CIRMMP) University of Florence Sesto Fiorentino 50019 Italy

6. Centre for Magnetic Resonance CERM University of Florence Sesto Fiorentino 50019 Italy

7. Monash Biomedicine Discovery Institute and Department of Biochemistry, and Molecular Biology Monash University Clayton VIC 3800 Australia

8. Department of Chemistry and Applied Biosciences ETH Zurich 8093 Zürich Switzerland

9. Bridge Institute Department of Chemistry University of Southern California. Los Angeles CA 90089 USA

10. Department of Biology and Biotechnology “Lazzaro Spallanzani” University of Pavia Pavia Italy

11. John Fulcher Neuro-oncology Laboratory Division of Brain Sciences Faculty of Medicine Imperial College London London W6 8RP UK

12. Leaders in Oncology Care 95 Harley Street London W1G 6AF UK

13. Centre for Haemato-Oncology Barts Cancer Institute Queen Mary University of London London UK

14. Monash Biomedicine Discovery Institute and Department of Pharmacology Monash University Clayton VIC 3800 Australia

15. Department of Biomedical Imaging and Image Guided Therapy Medical University of Vienna Vienna Austria

16. Ludwig Boltzmann Institute Applied Diagnostics General Hospital of Vienna Vienna Austria

17. Institute of Inorganic Chemistry Faculty of Chemistry University of Vienna Vienna Austria

Funder

Ministry of Education and Religious Affairs, Sport and Culture

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

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