Affiliation:
1. Univ Rouen Normandie, INSA Rouen Normandie, CNRS, Normandie Univ COBRA UMR 6014 Rouen F-76000 France
Abstract
AbstractNickel‐catalyzed intramolecular hydrosilylation can be efficiently achieved with high regio‐ and stereoselectivities through two distinct methodologies. The first approach utilizes a conventional method, involving the reduction of nickel salt (NiBr2‐2,2’‐bipyridine) using manganese metal. The second method employs a one‐step electrochemical reaction, utilizing the sacrificial anode process and NiBr2bipy catalysis. Both methods yield silylated heterocycles in good to high yields through a syn‐exo‐dig cyclization process. Control experiments and molecular electrochemistry (cyclic voltammetry) provided further insights into the reaction mechanism.
Funder
Université de Rouen
Région Normandie
Institut National des Sciences Appliquées Rouen
Institut de chimie
European Regional Development Fund
XL-Chem Graduate School of Research