Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence-Reference-Cited by-同舟云学术

Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence

Published:2021-05-18 Issue:35 Volume:27 Page:8985-8993
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Oehler Sebastian¹^ORCID,Catalano Marco¹^ORCID,Scapozza Ilario¹,Bigatti Martina²,Bassi Gabriele¹^ORCID,Favalli Nicholas¹^ORCID,Mortensen Michael R.¹^ORCID,Samain Florent²^ORCID,Scheuermann Jörg¹^ORCID,Neri Dario²^ORCID

Affiliation:

1. Department of Chemistry and Applied Biosciences ETH Zürich Vladimir-Prelog-Weg 3 8093 Zürich Switzerland

2. Philochem AG Libernstrasse 3 8112 Otelfingen Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Carlsbergfondet

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202100816

Reference53 articles.

1. Principles in the design of ligand-targeted cancer therapeutics and imaging agents

2. Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

3. Discovery of small molecule cancer drugs: Successes, challenges and opportunities

4. Impact of high-throughput screening in biomedical research

5. Encoded combinatorial chemistry.

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