Substrain-specific differences in bone parameters, alpha-2-macroglobulin circulating levels, and osteonecrosis incidence in a rat model

Author:

Carli Alberto V.123,Harvey Edward J.123,Azeddine Bouziane1,Gao Chan2,Li Yongbiao1,Li Ailian2,Sayegh Mireille1,Wang Huifen2,Nahal Ayoub4,Michel René P.4,Henderson Janet E.2,Séguin Chantal15

Affiliation:

1. Vascular; Biology Research Lab; Research Institute; McGill University Health Centre; C9 Montreal General Hospital; 1650 Cedar Avenue Montreal QC H3G 1A4 Canada

2. Bone Engineering Labs; Surgical Research; Research Institute; McGill University Health Centre, Montreal General Hospital; 1650 Cedar Avenue Montreal QC H3G 1A4 Canada

3. Department of Surgery; Division of Orthopaedic Surgery; McGill University Health Centre; B5 Montreal General Hospital; 1650 Cedar Avenue Montreal QC H3G 1A4 Canada

4. Department of Pathology, McGill University Health Centre (MUHC), C3 Montreal General Hospital, 1650 Cedar Avenue, Montreal, QC H3G 1A4; Canada and McGill University Health Centre (MUHC); Glen site, 1001 Décarie Blvd Montreal QC H4A 3J1 Canada

5. Department of Medicine; Division of Hematology and Oncology; McGill University Health Centre; Glen site, 1001 Décarie Blvd room D02-7519, Montreal QC H4A 3J1 Canada

Funder

Leukemia and Lymphoma Society

Fonds de Recherche du Québec - Santé

Yvon Boulanger Foundation

Canadian Institutes of Health Research

FRQS-sponsored Réseau de recherche en santé buccodentaire et osseuse (RSBO)

McGill University

NCE-MITACS Accelerate

RI-MUHC (CG)

Publisher

Wiley

Subject

Orthopedics and Sports Medicine

Reference46 articles.

1. Nontraumatic necrosis of bone (osteonecrosis);Mankin;N Engl J Med,1992

2. Schappert SM Rechsteiner EA 2008

3. Total hip arthroplasty after failed treatment for osteonecrosis of the femoral head;Rijnen;Orthop Clin North Am,2009

4. Current management options for osteonecrosis of the femoral head: part II, operative management;Amanatullah;Am J Orthop (Belle Mead NJ),2011

5. Avascular necrosis of the femoral head: vascular hypotheses;Kerachian;Endothelium,2006

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