A New Approach to 5-Thiosugars: 5-Thio-D-Gluconhydroximo-1,5-lactone, Synthesis and Evaluation as ?-Glucosidase Inhibitor
Author:
Publisher
Wiley
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis
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1. Inhibition of Emulsin byD-Gluconhydroximo-1,5-lactone and Related Compounds
2. Mimicking the glucosidase transition state: shape/charge considerations
3. D-Gluconhydroximo-1,5-lactam and RelatedN-Arylcarbamates Theoretical Calculations, Structure, Synthesis, and Inhibitory Effect on ?-Glucosidases
4. Mechanistic consequences of mutation of the active site nucleophile Glu 358 in Agrobacterium .beta.-glucosidase
5. Enzyme-catalyzed aldol condensation for asymmetric synthesis of azasugars: synthesis, evaluation, and modeling of glycosidase inhibitors
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