Nucleic Acid Analogs with Constraint Conformational Flexibility in the Sugar-Phosphate Backbone ?Tricyclo-DNA?. Part 1. Preparation of [(5?R,6?R)-2?-deoxy-3?,5?-ethano-5?,6?-methano-?-D-ribofuranosyl]thymine and -adenine, and the corresponding phosphoramidites for oligonucleotide synthesis
Author:
Publisher
Wiley
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis
Reference24 articles.
1. Chemisch modifizierte Oligonucleotide als Sonden und Agentien
2. Chemically Modified Oligonucleotides as Probes and Inhibitors
3. Antisense oligonucleotides: a new therapeutic principle
4. Current concepts in antisense drug design
5. Antisense Oligonucleotides
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1. Synthesis and properties of oligonucleotides bearing thymidine derivatives with 1,6-dioxaspiro[4.5]decane skeleton;Bioorganic & Medicinal Chemistry;2021-02
2. NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance;Nucleic Acids Research;2019-03-27
3. 6’-Fluoro[4.3.0]bicyclo nucleic acid: synthesis, biophysical properties and molecular dynamics simulations;Beilstein Journal of Organic Chemistry;2018-12-20
4. Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes;Methods in Molecular Biology;2016
5. 2′-Fluorination of Tricyclo-DNA Controls Furanose Conformation and Increases RNA Affinity;Organic Letters;2015-04-02
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