A synergistic interaction between HDAC‐ and PARP inhibitors in childhood tumors with chromothripsis-Reference-Cited by-同舟云学术

A synergistic interaction between HDAC‐ and PARP inhibitors in childhood tumors with chromothripsis

Published:2022-04-28 Issue:4 Volume:151 Page:590-606
ISSN:0020-7136
Container-title:International Journal of Cancer
language:en
Short-container-title:Intl Journal of Cancer

Author:

Khalid Umar¹²^ORCID,Simovic Milena¹²,Hammann Linda A.¹²,Iskar Murat³,Wong John K. L.³,Kumar Rithu¹,Jugold Manfred⁴,Sill Martin⁵⁶,Bolkestein Michiel¹,Kolb Thorsten¹,Hergt Michaela¹,Devens Frauke¹,Ecker Jonas⁵⁷,Kool Marcel⁵⁶⁷,Milde Till⁵⁸⁹,Westermann Frank⁵¹⁰,Benner Axel¹¹,Lewis Joe¹²,Dietrich Sascha¹³,Pfister Stefan M.⁵⁶⁹,Lichter Peter³,Zapatka Marc³,Ernst Aurélie¹

Affiliation:

1. Group Genome Instability in Tumors German Cancer Research Center (DKFZ) Heidelberg Germany

2. University of Heidelberg Heidelberg Germany

3. Division of Molecular Genetics German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) Heidelberg Germany

4. Core Facility, Small Animal Imaging Center, DKFZ Heidelberg Germany

5. Hopp Children's Cancer Center (KiTZ) Heidelberg Germany

6. Pediatric Neurooncology German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) Heidelberg Germany

7. Princess Máxima Center for Pediatric Oncology Utrecht The Netherlands

8. Clinical Cooperation Unit Pediatric Oncology German Cancer Research Center and German Consortium for Translational Cancer Research Heidelberg Germany

9. KiTZ Clinical Trial Unit, Department of Pediatric Hematology and Oncology Heidelberg University Hospital Heidelberg Germany

10. Neuroblastoma Genomics German Cancer Research Center (DKFZ) Heidelberg Germany

11. Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany

12. European Molecular Biology Laboratory Heidelberg Germany

13. Department of Medicine V Hematology, Oncology and Rheumatology, University of Heidelberg Heidelberg Germany

Funder

Fritz Thyssen Stiftung

Wilhelm Sander-Stiftung

Publisher

Wiley

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.34027

Reference34 articles.

1. Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

2. Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

3. The landscape of chromothripsis across adult cancer types

4. Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

5. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

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