Enhanced Hepatic Functions of Genetically Modified Mouse Hepatoma Cells by Spheroid Culture for Drug Toxicity Screening-Reference-Cited by-同舟云学术

Enhanced Hepatic Functions of Genetically Modified Mouse Hepatoma Cells by Spheroid Culture for Drug Toxicity Screening

Published:2017-09-06 Issue:10 Volume:12 Page:1700274
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnol. J.

Author:

Sarkar Joyita¹,Kumari Jyoti¹,Tonello Jane M.²,Kamihira Masamichi²,Kumar Ashok¹

Affiliation:

1. Department of Biological Sciences and Bioengineering & Centre for Environmental Sciences and EngineeringIndian Institute of Technology KanpurKanpur 208016India

2. Department of Chemical EngineeringKyushu UniversityFukuokaJapan

Funder

Department of Science and Technology-Japan Society for the Promotion of Science, DST-JSPS

Department of Biotechnology, Ministry of Science and Technology

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.201700274

Reference27 articles.

1. Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity

2. Drug-Induced Liver Injury

3. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

4. Managing the challenge of chemically reactive metabolites in drug development

5. Hepatic Cell Lines for Drug Hepatotoxicity Testing: Limitations and Strategies to Upgrade their Metabolic Competence by Gene Engineering

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