BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture
Author:
Affiliation:
1. The Novo Nordisk Foundation Center for BiosustainabilityTechnical University of Denmark Kgs. Lyngby 2800 Denmark
2. Department of Biological SciencesKAIST Daejeon 34141 Republic of Korea
Funder
Novo Nordisk Fonden
Publisher
Wiley
Subject
Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.201900130
Reference48 articles.
1. The art of CHO cell engineering: A comprehensive retrospect and future perspectives
2. In search of expression bottlenecks in recombinant CHO cell lines—a case study
3. ER-associated degradation: Protein quality control and beyond
4. ER stress-induced cell death mechanisms
5. Non-invasive UPR monitoring system and its applications in CHO production cultures
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