Low oxygen tension favored expansion and hematopoietic reconstitution of CD34+CD38−cells expanded from human cord blood-derived CD34+Cells

Author:

Wang Ziyan1,Du Zheng1,Cai Haibo1,Ye Zhaoyang1,Fan Jinli1,Tan Wen-Song1

Affiliation:

1. State Key Laboratory of Bioreactor Engineering; East China University of Science and Technology; Shanghai China

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences Key Project

Applied and Basic Research Foundation of Yunnan Provincial Science and Technology Commission

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference36 articles.

1. Hematopoietic stem cells, their niche, and the concept of co-culture systems: A critical review;Vaidya;J. Stem Cells,2015

2. Bone-marrow haematopoietic-stem-cell niches;Wilson;Nat. Rev. Immunol.,2006

3. Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes;Mostafa;Exp. Hematol.,2001

4. Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro;Jing;Haematologica,2012

5. Concise review: The role of oxygen in hematopoietic stem cell physiology;Jez;J. Cell. Physiol.,2015

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