Steric Accessibility of the Cleavage Sites Dictates the Proteolytic Vulnerability of the Anti‐HIV‐1 Antibodies 2F5, 2G12, and PG9 in Plants-Reference-Cited by-同舟云学术

Steric Accessibility of the Cleavage Sites Dictates the Proteolytic Vulnerability of the Anti‐HIV‐1 Antibodies 2F5, 2G12, and PG9 in Plants

Published:2019-11-08 Issue:3 Volume:15 Page:1900308
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnol. J.

Author:

Puchol Tarazona Alejandro A.¹,Lobner Elisabeth²,Taubenschmid Yvonne¹,Paireder Melanie¹,Torres Acosta Juan A.¹,Göritzer Kathrin¹,Steinkellner Herta¹,Mach Lukas¹^ORCID

Affiliation:

1. Department of Applied Genetics and Cell BiologyUniversity of Natural Resources and Life Sciences Muthgasse 18 A‐1190 Vienna Austria

2. Department of BiotechnologyUniversity of Natural Resources and Life Sciences Muthgasse 11 A‐1190 Vienna Austria

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.201900308

Reference52 articles.

1. Combination therapy with anti-HIV-1 antibodies maintains viral suppression

2. Global Shape and Ligand Binding Efficiency of the HIV-1-neutralizing Antibodies Differ from Those of Antibodies That Cannot Neutralize HIV-1

3. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

4. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

5. Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants

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